Fig. 4.From: A novel apolipoprotein E mutation, ApoE Ganzhou (Arg43Cys), in a Chinese son and his father with lipoprotein glomerulopathy: two case reportsHistological analysis of the renal biopsy specimens in case 2. A Hardened glomerulus under light microscope (PASM staining, ×200). B Glomerulus with segmental sclerosis under light microscope (PASM staining, ×200). C Immunofluorescence microscopy results showing positive ApoE. D and E Electron microscopy results showing capillary endothelial cells with obvious vacuolar degeneration, and a large number of lipid vacuolar protein substances in the cavity (scale bar, 2 μm for D and 0.5 μm for E)Back to article page