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Table 2. Six reported cases of IFN-β-induced sarcoidosis [29,30,31,32,33,34].

From: Interferon-induced sarcoidosis with uveitis as the initial symptom: a case report and review of the literature

  

Patients (n)

Proportion of patients (%)

Primary diseases

Multiple sclerosis

5

88.3

 

Melanoma

1

16.7

Sex

Male

6

33.3

 

Female

2

66.7

Age of sarcoidosis onset (mean ± standard deviation)

Overall: 40.2 ± 11.1 years

Men: 48.0 ± 18.4 years

Women: 36.3 ± 6.8 years

Period until onset

53.8 months

(range, 5–156 months)

Organ involvement

Lung*

6

100

 

Lymphadenopathy

Hilar

5

83.3

 

Mediastinal

4

66.6

 

Abdominal

1

16.6

 

Skin, spleen

Each 2

Each 33.3

 

Liver

1

16.6

Therapy

Discontinuation of IFN

6

100

 

Oral steroid

5

83.3

 

Other medicine

3

50

Outcome

Resolution

4

66.7

 

Improvement

1

16.6

 

No change

1

16.6

  1. IFN interferon, n number
  2. *With or without mediastinal and/or hilar lymphadenopathy