Table 1 Previous reports of cerebellar degeneration secondary to PSS
From: Cerebellar degeneration in primary Sjögren syndrome: a case report
Age | Sex | Neurologic deficits | MRI brain findings | Autoantibody | Treatment received | Treatment effect | |
|---|---|---|---|---|---|---|---|
Terao et al. 1994 | 61 | M | Ataxia, dysarthria, vertigo | Cerebellar and frontal lobe atrophy, multiple high-signal-intensity lesions | Antineuronal Ab (+) | Steroid | + |
Owada et al. 2002 | 55 | F | Motor weakness, ataxia, sensory disturbance, depression, apathy | Cerebellar and cerebral cortex atrophy | Antineuronal Ab (+) | Steroid | − |
Kim et al. 2012 | 46 | F | Gait and limb ataxia, depression, delusion | Cerebellar atrophy with an enlarged fourth ventricle and cisterna magna | Paraneoplastic Ab (−) | Steroid | − |
Farhat et al. 2016 | 30 | F | Cerebellar ataxia worsening over 4 years associated with tremor of the limbs and the head | Bilateral hyperintensities affecting periventricular white matter, with marked cerebellar atrophy | Paraneoplastic Ab (−) | Steroid and cyclophosphamide | − |
Maciel et al. 2017 | 36 | F | Ataxia, dysarthria | Cerebellar atrophy | Not done | Steroid and cyclophosphamide | − |
Heidary et al. 2018 | 22 | F | Ataxia with tremor of four limbs | Cerebellar atrophy | Not done | Steroid and cyclophosphamide | + |