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Table 1 Comparison of clinical features with cases described in the literature

From: Severe sequelae in bilateral acute iris transillumination syndrome secondary to the use of oral moxifloxacin: a case report

Author (year)

Number of cases

Time between first dose and onset of symptoms (days)

Empiric treatment

PCR for herpetic etiology study

Bilateral compromise

Anterior chamber cellularity

Transillumination defects

Pigment dispersion at gonioscopy

IOP

OD; OS (mmHg)

BCVA

OD; OS

Posterior subcapsular opacity

Glaucoma

Ahmed glaucoma valve

Rivera-Valdivia (present case)

1

14

Systemic antiviral and IMT

HSV (−)

VZV (−)

CMV (−)

EBV (−)

Mycobacteria (−)

Toxoplasma (−)

+

+

+

+

30; 28

20/20; 20/40

+

+

+

Plaza-Ramos et al. (2018)

1

42

+

+

+

18; 18

20/20; 20/40

Rangel et al. (2017)

1

10

+

+

+

12; 12

20/20

Broens et al. (2016)

1

13

+

+

+

16; 16

20/20

Knape et al. (2013)

1

3

HSV (−)

VZV (−)

CMV (−)

+

+

+

35; 35

20/30; 20/40

ND

ND

Duncombe et al. (2013)

1

11

Systemic antiviral

HSV (−)

VZV (−)

CMV (−)

EBV (−)

+

+

+

50; 28

20/25

Nascimento et al. (2013)

3

60–90

+ (2 pt)

+ (1 pt)

+

+ (1 pt)

14; 14

16; 16

12; 12

20/20; 20/20

20/20; 20/20

20/20; 20/30

Morshedi et al. (2012)

2

15–18

+

+

+

+

15; 26

15; 17

20/30; 20/40

20/20; 20/20

+ (1 pt)

Willermain et al. (2010)

1

15

Herpes viruses (−)

+

+

+

+

46; 46

20/200; 20/200

Wefers Bettink-Remeijer et al. (2009)

5

10–14

HSV (1 pt +)

+

+ (2 pt)

+

ND

ND

ND

ND

ND

Bringas Calvo et al. (2004)

1

10

+

+

+

+

9; 8

20/25; 20/30

  1. PCR polymerase chain reaction, IMT immunomodulatory therapy, IOP intraocular pressure, OD right eye, OS left eye, BCVA best corrected visual acuity, ND not described, pt patient(s)