Fig. 1From: Megaloblastic anemia-related iron overload and erythroid regulators: a case reportProposed integrative interpretation of the results obtained from this case report. a May–Grünwald Giemsa staining of a bone-marrow smear showing hypercellularity (left) and intense basophilic megaloblasts (right, arrows). b Peripheral blood smear revealing increased neutrophil cell volume with a hypersegmented nucleus. c Hypothetical mechanism of the pathogenesis of iron overload in megaloblastic anemia. Relative changes in the size of the protein names represent their down- or upregulation. ERFE erythroferrone, GDF15 growth differentiation factor-15Back to article page