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Fig. 4 | Journal of Medical Case Reports

Fig. 4

From: Complete remission in metastatic primary malignant melanoma of the esophagus with nivolumab: a case report

Fig. 4

Low-power (a) and high-power (b) magnification of esophageal biopsies showed melanin granules within tumor cells and melanoblasts in the interstitium. Immunohistochemistry was positive for melan A (c). In situ lesions were also observed, suggesting that the esophagus was the primary site (d). Immunohistochemistry for the resected bladder specimen was positive for melan A (e), SOX10 (f), and p53 (g). The MIB-1 proliferation index was 80% (h)

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Journal of Medical Case Reports

ISSN: 1752-1947