|
Drug
|
SPT
|
IDT
|
|---|
|
Concentration of the stock solution (mg/ml)
|
Results
|
Concentration of the stock solution (mg/ml)
|
Results
|
Wheal (mm)
|
Flare (mm)
|
|---|
|
Saline
|
9
|
−
|
9
|
−
| | |
|
Histamine
|
10
|
+
|
0.01
|
+
|
15
|
40
|
|
Sugammadex
|
100
|
−
|
10
|
+
|
12
|
20
|
|
Propofol
|
10
|
−
|
1
|
−
| | |
|
Rocuronium
|
10
|
−
|
0.1
|
−
| | |
|
Remifentanil
|
0.05
|
−
|
0.005
|
−
| | |
|
ABPC/SBT
|
20/10
|
−
|
2/1
|
−
| | |
|
Fentanyl
|
0.05
|
−
|
0.005
|
−
| | |
|
Flurbiprofen
|
10
|
−
|
1
|
−
| | |
|
Acetaminophen
|
10
|
−
|
1
|
−
| | |
- Saline and histamine were used as negative and positive controls, respectively. Skin prick test (SPT) was started with a 100-fold dilution of stock solution, and a 10-fold dilution and stock solution were inspected. However, none of the drugs except histamine showed a positive result. Subsequently, intradermal tests (IDTs) were performed. After confirming a positive reaction for histamine and a negative reaction for saline, sugammadex showed a positive reaction at a 100-fold dilution of the stock solution, that is, 0.1 mg/ml. Other tested agents did not result in a positive reaction with a 100-fold dilution of the stock solution. ABPC/SBT ampicillin/sulbactam
