Hereditary pheochromocytoma/paraganglioma syndrome with a novel mutation in the succinate dehydrogenase subunit B gene in a Japanese family: two case reports

Table 3 Summary of reported ideas of surveillance screening for patients with SDHB mutation

Refs.	Year	Clinical review (physical examination, BP, PR)	Biochemical test	Imaging test	Age to start surveillance (years)
[4]	2006	Frequency not stated	Annual	MRI or CT from neck to pelvis every 2 years Consider ¹⁸F-DOPA-PET	10
[35]	2014	Every 6–12 months	Annual	MRI or CT from thorax to pelvis every 6–24 months MRI or CT of skull base and neck every 2–4 years MIBG scintigraphy every 2–4 years	5–10
[32]	2019	Annual	Annual	MRI of abdomen every year MRI from skull base to pelvis every 2 years	5
[36]	2019	Annual	Annual	MRI from skull base to pelvis every 2–3 years	5 (10 as to MRI)
[37]	2019	Every 6 months	Annual	Rapid whole-body MRI every 2 years	5 years before the earliest age of onset in the family

BP, blood pressure; PR, pulse rate; MRI, magnetic resonance imaging; CT, computed tomography; MIBG, metaiodobenzylguanidine; 18F-DOPA-PET, 6-[18F]-fluoro-L-3,4-dihydroxyphenylalanine positron emission tomography

ISSN: 1752-1947