Fig. 1

Patient’s response to methimazole (MMI) treatment following three recurrences of Graves’ hyperthyroidism. She stopped treatment on three occasions; after each time, hyperthyroidism recurred but was appropriately managed by re-initiating MMI therapy, with subsequent normalization of serum free thyroxine (fT4), triiodothyronine (T3), thyroid stimulating hormone (TSH) and TSH receptor antibody (TRAb) each time. The metimazole dose gradually decreased to a minimum of 1.25 mg daily