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Table 3 Results of laboratory tests performed to diagnose cold agglutinin disease and determine background infections

From: Cold agglutinin-induced hemolytic anemia during room temperature fluid resuscitation: a case report

Laboratory tests

Patient’s results/values

Reference range

Direct Coombs test

Positive

 

Indirect Coombs test

Negative

 

CA titer at 4 ℃

1:8192

1:< 256

EBV VCA IgM

< 10

< 10

EBV VCA IgG

160

< 10

EBNA

20

< 10

CMV antigenemia

Negative

 

CMV IgM

Negative

 

CMV IgG

Negative

 

Mycoplasma pneumoniae PA titer

< 40

< 40

Mycoplasma pneumoniae LAMP

Negative

 
  1. EBV VCA Epstein–Barr virus viral capsid antigen, EBNA EBV nuclear antigen, CMV Cytomegalovirus, Ig immunoglobulin, PA particle agglutination, LAMP loop-mediated isothermal amplification