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Fig. 1 | Journal of Medical Case Reports

Fig. 1

From: Atypical anti-glomerular basement membrane glomerulonephritis in a patient with metastatic melanoma treated with mitogen-activated protein kinase and immune checkpoint inhibitors: a case report

Fig. 1

a Chronic active interstitial nephritis with focal cellular crescents and linear IgG immunoglobulin deposition. Widespread acute tubular injury with luminal dilatation and flattened epithelium. A glomerulus demonstrates segmental sclerosis and capsular adhesion, possibly and previous crescent (arrow) (hematoxylin and eosin [H&E], original magnification 40×). b Glomerulus with cellular crescent (periodic acid–Schiff [PAS], original magnification 200×). c Immunofluorescence microscopy demonstrates linear staining for Immunoglobulin G along peripheral capillary loops of all glomeruli (original magnification 200×), also for positive linear IgG3+, IgA 2+, Kappa 2+, Lambda 2 anti-glomerular basement membrane glomerulonephritis (not shown)

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Journal of Medical Case Reports

ISSN: 1752-1947