Figure 2.

a Muscle magnetic resonance image with STIR sequence in the axial plane. The image shows symmetric thickening and high signal intensity in the peripheral deep fasciae (arrows) and intermuscular fasciae (arrowheads), mainly in the posterior muscle compartment of the thigh. b Deep skin biopsy (magnification 40×) showing thickening of the fascia due to lymphocyte and plasma cell infiltration. We observed only one eosinophil granulocyte (arrow). c Trends in hepatic enzyme elevation and standardization, with platelet counts, during the course of this case of Shulman disease. AST Aspartate aminotransferase, ALT alanine aminotransferase, AP alkaline phosphatase, GGT gamma-glutamyltransferase