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Fig. 1 | Journal of Medical Case Reports

Fig. 1

From: Dichotomic response to interleukin-6 blockade in idiopathic multicentric Castleman disease: two case reports

Fig. 1

Imaging and pathological findings of iMCD case 1 and case 2. Case 1 CT/PET-scan examination: contrast-enhancing peri-pancreatic and retrocaval adenopathies (a); Case 1 formalin-fixed paraffin-embedded (FFPE) lymph node: follicular regression (hematoxylin and eosin [H&E] staining, b) and plasmacytosis (CD138 staining, c). Case 2 FFPE lymph node (H&E staining, d): germinal center fragmentation (Giemsa staining, e); plasmacytosis with light chains impaired ratio (kappa staining, f). Case 2 bone marrow biopsy showing reactive plasmacytosis (CD138 staining, g). PET: computed tomography/positron emission tomography; FFPE tissue: Formalin-Fixed Paraffin-Embedded tissue; iMCD: Idiopathic multicentric Castleman disease; H&E: Hematoxylin and eosin

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Journal of Medical Case Reports

ISSN: 1752-1947