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Fig. 2 | Journal of Medical Case Reports

Fig. 2

From: Steroid-refractory dermatologic and pulmonary toxicity in a patient on rituximab treated with pembrolizumab for progressive urothelial carcinoma: a case report

Fig. 2

a Site of punch biopsy on patient’s upper back. b At scanning magnification, there is a basket-weave stratum corneum with a subepidermal split and mild superficial perivascular inflammation (hematoxylin and eosin [H&E], original magnification ×10). c On higher magnification, there is an interface dermatitis with numerous scattered dyskeratotic keratinocytes and confluent partial- to full-thickness epidermal necrosis. Lymphocytes and eosinophils are present within the subepidermal split. There is a mild superficial perivascular lymphocytic infiltrate with scattered eosinophils (H&E, original magnification ×40)

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