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Table 1 Laboratory results for the patient

From: Nivolumab-induced hypophysitis followed by acute-onset type 1 diabetes with renal cell carcinoma: a case report

Variable

Reference range

Complete blood count

 

 White blood cell count (/μl)

5160

47.0–87.0

 Red blood cells (×104/μl)

383

370–490

 Hemoglobin (g/dl)

9.8

11.0–15.0

 Hematocrit (%)

29.4

35.0–45.0

 Platelet count (×104/μl)

30.4

15.0–35.0

Biochemistry

 

 Total protein (g/dl)

6.1

6.5–8.2

 Albumin (g/dl)

3.1

3.5–5.5

 Blood urea nitrogen (mg/dl)

11.4

7.0–20.0

 Creatinine (mg/dl)

1.46

0.5–1.0

 AST (U/l)

38

10–35

 ALT (U/l)

13

5–40

 GGTP (U/l)

17

0–30

 Na (mmol/l)

120

135–146

 K (mmol/l)

4.6

3.5–4.6

 Cl (mmol/l)

88

96–110

 Plasma osmolality (mOsm/kg)

292

275–295

Diabetes-related examination

  

 Glucose (mg/dl)

112

70–109

 HbA1c (on admission) (%)

7.0

4.6–6.2

 Serum CPR (ng/ml)

2.37

0.43–2.35

Endocrinological examination

  

 ACTH (pg/ml)

6.64

7.2–63.3

 Cortisol (μg/dl)

0.4

2.3–19.4

 GH (ng/ml)

1.61

0.28–1.64

 IGF-1 (ng/ml)

66

76–228

 PRL (ng/ml)

38.5

4.3–13.7

 LH (mIU/ml)

11.4

0.57–12.07

FSH (mIU/ml)

7.6

0.95–11.95

 Testosterone (ng/ml)

477.5

142.4–923.1

 AVP (pg/ml)

0.8

0.3–4.2

 TSH (μIU/ml)

2.14

0.35–4.94

 FT3 (pg/ml)

3.71

1.71–3.71

 FT4 (ng/dl)

1.03

0.70–1.48

Urinalysis

  

 U-Osmolality (mOsm/kg)

178

767–1628

 U-Na (mmol/l)

28

 

 U-K (mmol/l)

17

 

 U-Cl (mmol/l)

29

 

 U-Creatinine (mg/dl)

29

 
  1. AST aspartate aminotransferase, ALT alanine transaminase, GGTP gamma-glutamyltransferase, HbA1c hemoglobin A1c, CPR C-peptide immunoreactivity, ACTH adrenocorticotropic hormone, GH growth hormone, IGF1 insulin-like growth factor, PRL prolactin, LH luteinizing hormone, FSH follicle-stimulating hormone, AVP arginine vasopressin, TSH thyroid-stimulating hormone, FT3 free triiodothyronine, FT4 free thyroxin