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Table 1 Clinicopathological features of reported cases of mediastinal low-grade fibromyxoid sarcoma

From: Low-grade fibromyxoid sarcoma incidentally discovered as an asymptomatic mediastinal mass: a case report and review of the literature

Reference/year of publication

Age/Sex

Tumor size (cm)

Primary location

Histological findings

Intervention performed

Outcomes

Takanami et al. [2]

1999

35/M

9 × 5.5 × 3

Anterior mediastinum

Bland-appearing fibroblastic spindle cells in fibrous and

myxoid areas in a whorled pattern

Surgical resection

Recurred after 9 years. Alive without remission or residual symptoms in 2 months of follow-up

Galetta et al. [3]

2004

41/M

8 × 4 × 3

Behind the thymus

Vascularized myxoid sarcoma with hyalinized collagenous and spindled-shaped areas

Surgical resection

Alive without remission or residual symptoms in 35 months of follow-up

Jakowski et al. [4]

2008

44/F

12

Arose from the right epicardium at the atrioventricular groove adherent to the right ventricular free wall

Admixture of hypocellular myxoid and hyper-cellular spindle cell areas in a collagenous stroma with numerous large hyalinized collagen rosettes

Surgical resection

Alive without remission or residual symptoms in 7 months of follow-up

Gulhan et al. [5]

2012

25/F

17 × 13 × 11

Posterior mediastinum, compressing on the anterior mediastinal formations

Lesion formed by spindle-shaped cells was visible in the myxoid and hyalinized stroma. Giant collagen rosettes were also visualized

Surgical resection

Discharged in a stable condition after 11 days and no subsequent follow-up

Maedah et al. [6]

2009

2 cases

19/F

50/M

23.5 × 10 × 21.5

13 × 13 × 13

CT measurements

20 × 10 × 21

11 × 7.2 × 11.5

Case 1: Anterior mediastinum

Case 2: Right superior mediastinum

Three distinct zones were noted: hyper-cellular zones with islands of collagen fibers, hypo-cellular zones with abundant myxoid stroma, and prominently hyalinized zones

Surgical resection of all the cases

C1: Recurrence of anterior mediastinal mass after 5 years

C2 Alive without remission or recurrence in 5 years of follow-up

Pervez et al. [7]

2019

32/M

11

Tumor arising from the parietal pleura with attachments to both lung and diaphragm

Tumor was composed of uniform and bland-appearing spindle cells interspersed among large areas of hyalinized rosettes

Surgical resection

No follow-up reported

  1. CT: computed tomography