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Table 2 Laboratory data at the time of diagnosis of TAFRO syndrome

From: A severe case of thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly syndrome with myocardial and skeletal muscle calcification despite hypocalcemia: a case report

Complete blood cell count Blood chemistry Immunologic test
WBC 23,600 /μL Albumin 1.5 g/dL IgG 1385 mg/dL
Band 6 % T.Bil 0.4 mg/dL IgG4 66 mg/dL
Seg 88 % AST 33 IU/L IgA 187 mg/dL
Lympho 3 % ALT 12 IU/L IgM 62 mg/dL
Mono 3 % LDH 471 IU/L ANA <40 times
RBC 348 104/μL γ-GTP 266 IU/L anti-RNP Ab  
Hgb 9.9 g/dL ALP 400 IU/L anti-ds-DNA IgG  
MCV 86.8 fL BUN 119.5 mg/dL anti-SS-A Ab  
Platelet 7.5 104/μL Cr 7.77 mg/dL RF <3 IU/mL
ESR 87 mm/hr CRP 36.35 mg/dL PR3-ANCA <1 IU/mL
    Ferritin 1873 ng/mL MPO-ANCA <1 IU/mL
    ACE 7.6 IU/L Coombs test  
    Haptoglobin 311 mg/dL PA-IgG 70 ng/107cells
Infectious diseases     ADAMTS-13 28 %
EBV VCA IgG +   Coagulation system anti-GBM Ab <2 U/mL
EBV VCA IgM -   PT 19 Sec sIL-2R 1260 U/mL
EBNA IgG +   PT-INR 1.59   IL-6 65.1 pg/mL
CMV C7-HRP -   APTT >80 Sec VEGF 1030 pg/mL
    (Standard: 26-36)     
HIV antigen/Ab -   Fibrinogen >600 mg/dL    
HHV-8 DNA (WBC106cells) <20   AT-III 58 %    
IGRA   FDP 66 μg/mL    
  1. WBC White blood cell, RBC Red blood cell, Hgb Hemoglobin, MCV Mean corpuscular volume, ESR Erythrocyte sedimentation rate, EBV Epstein–Barr virus, VCA Virus capsid antigen, EBNA Epstein–Barr virus nuclear antigen, CMV Cytomegalovirus, HIV Human immunodeficiency virus, Ab Antibody, HHV-8 Human herpesvirus-8, IGRA Interferon-gamma releasing assay, T.Bil Total Bilirubin, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LDH Lactate dehydrogenase, γ-GTP Gamma-glutamyl transpeptidase, ALP Alkaline phosphatase, BUN Blood urea nitrogen, Cr Creatinine, CRP C-reactive protein, ACE Angiotensin-converting enzyme, PT Prothrombin time, PT-INR Prothrombin time-international normalized ratio, APTT Activated partial thromboplastin time, AT-III Antithrombin III, FDP Fibrin/fibrinogen degradation products, ANA Antinuclear antibody, anti-RNP-antibody Anti-ribonucleoprotein antibody, anti-ds-DNA IgG Anti-double-stranded deoxyribonuclein acid immunoglobulin G, anti-SS-A antibody Anti-Sjören's syndrome A antibody, RF Rheumatoid factor, PR3-ANCA Proteinase 3-anti-neutrophil cytoplasmic antibody, MPO-ANCA Myeloperoxidase-anti-neutrophil cytoplasmic antibody, PA-IgG Platelet-associated immunoglobulin G, anti-GBM antibody Anti-glomerular basement membrane antibody, sIL-2R Soluble interleukin-2 receptor, IL-6 Interleukin-6, VEGF Vascular endothelial growth factor