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Table 1 A review of studies of Cy-induced hemorrhagic cystitis in adult or pediatric allogeneic stem cell transplant patients treated successfully with hyperbaric oxygen

From: The utility of hyperbaric oxygen therapy in post-transplant cyclophosphamide-induced hemorrhagic cystitis: a case report and review of the literature

Study identifier Study design Inclusion criteria/study groups Number of patients Median age (year) Gender (male: female) Cyclophosphamide dose Acute GVHD percentage Infection percentage Response rate (%)
K. Hattori et al. [11] Case report HC after allogeneic SCT in children 2 7 2:00 60 mg/kg/day for 2 days, 50 mg/kg/day for 4 days 0 0 100
S. Cesaro et al. [12] Cross sectional HC in pediatric patients after SCT 38 10.8 4:01 Not disclosed 20 71 84
M. Payandeh et al. [13] Case report HC after allogeneic SCT in AML patient 1 40 1:00 Not disclosed 100 0 100
  1. In all reported cases, cyclophosphamide (Cy) was used as part of the conditioning regimen, not as post-transplantation Cy (PTCy). HC hemorrhagic cystitis, SCT stem cell transplant, AML acute myeloid leukemia, GVHD graft-versus-host disease