Effective treatment of osmotic demyelination syndrome with plasmapheresis: a case report and review of the literature

Table 3. Summary of case reports describing plasmapheresis used to treat ODS.

Age and gender of the patient	Clinical features	MRI findings		Day of initiation of plasmapheresis	No. of cycles/volume exchanged	Outcome		References
Age and gender of the patient	Clinical features	Pontine	Extra-pontine	Day of initiation of plasmapheresis	No. of cycles/volume exchanged	Clinical	Radiological	References
29 F	Tetraparesis, areflexia, bulbar dysfunction	+	−	NA	24,700 mL	Partial	Unchanged	[8]
20 F	Spastic tetraparesis, bulbar dysfunction	+	−	NA	5243 mL	Partial	Unchanged	[8]
30 F	Tetraparesis, pseudo-bulbar palsy, nystagmus	+	−	NA	18,270 mL	Complete	Unchanged	[8]
59 F	Pseudo-bulbar palsy, flaccid tetraplegia, ophthalmoplegia, hyper-reflexia	+	−	A week after the onset of neurological manifestations	37,300 mL	Partial	Unchanged	[9]
40 F	Tetraparesis, pseudo-bulbar palsy, diplopia	+	−	Immediately after MRI confirmation of ODS	4394 mL	Partial	NA	[10]
71 F	Spastic tetraparesis, hyper-reflexia, dysphagia	+	+	23rd day after rapid sodium correction	3840 mL	Complete	The signals were reduced in size but remained	[6]
50 F	Drowsy, spastic tetraparesis, areflexia, bulbar dysfunction	+	−	20th day after the onset of neurological manifestations	7 cycles	Complete	NA	(7)

ISSN: 1752-1947