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Table 3. Summary of case reports describing plasmapheresis used to treat ODS.

From: Effective treatment of osmotic demyelination syndrome with plasmapheresis: a case report and review of the literature

Age and gender of the patient Clinical features MRI findings Day of initiation of plasmapheresis No. of cycles/volume exchanged Outcome References
Pontine Extra-pontine Clinical Radiological
29 F Tetraparesis, areflexia, bulbar dysfunction + NA 24,700 mL Partial Unchanged [8]
20 F Spastic tetraparesis, bulbar dysfunction + NA 5243 mL Partial Unchanged [8]
30 F Tetraparesis, pseudo-bulbar palsy, nystagmus + NA 18,270 mL Complete Unchanged [8]
59 F Pseudo-bulbar palsy, flaccid tetraplegia, ophthalmoplegia, hyper-reflexia + A week after the onset of neurological manifestations 37,300 mL Partial Unchanged [9]
40 F Tetraparesis, pseudo-bulbar palsy, diplopia + Immediately after MRI confirmation of ODS 4394 mL Partial NA [10]
71 F Spastic tetraparesis, hyper-reflexia, dysphagia + + 23rd day after rapid sodium correction 3840 mL Complete The signals were reduced in size but remained [6]
50 F Drowsy, spastic tetraparesis, areflexia, bulbar dysfunction + 20th day after the onset of neurological manifestations 7 cycles Complete NA (7)
  1. F female, NA data not available, + presence of changes, − absence of changes