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Table 1 Laboratory and urinalysis data findings before and after regimen of orally administered vibegron

From: Urodynamic effectiveness of a beta-3 adrenoreceptor agonist (vibegron) for a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity: a case report

Laboratory test

Before vibegron

After vibegron

Reference range

Units

Results

Results

WBC

12.5

6.0

3.3–8.6

× 103/µL

RBC

4.54

4.51

3.86–4.92

× 106/µL

Hb

12.7

12.8

11.6–14.8

g/dL

HCT

37.2

38.4

35.1–44.4

%

PLT

248

328

158–348

× 103/µL

TP

7.3

6.9

6.6–8.1

g/dL

ALB

4.4

4.8

4.1–5.1

g/dL

AST

28

23

13–30

IU/L

ALT

12

13

7–23

IU/L

LDH

228

216

124–222

IU/L

ALP

469

706

106–322

IU/L

CRE

0.34

0.39

0.46–0.79

mg/dL

BUN

8.6

11.1

8–20

mg/dL

UA

6.1

2.9

2.6–5.5

mg/dL

Na

138

138

138–145

mmol/L

K

3.8

4.2

3.6–4.8

mmol/L

CL

100

103

101–108

mmol/L

Ca

9.9

9.6

8.8–10.1

mg/dL

Laboratory test

Before vibegron

After vibegron

Reference range

Units

Results

Results

Urinalysis

 Color

Yellow

Yellow

Yellow

 

 Clarity

Cloudy

Cloudy

Clear

 

 Specific gravity

1.017

1.021

1.003–1.030

 

 pH

7.5

8.0

4.5–8.0

 

 Urobilinogen

Normal

Normal

Normal

 

 Bilirubin

Negative

 

 Leukocytes

3+

1+

Negative

 

 Nitrite

+

+

Negative

 

 Blood

Negative

 

 Protein

+−

Negative

 

 Glucose

Negative

 

 Ketone

Negative

 

Urine microscopy

 Red blood cells

5–9

1–4

Negative

/hpf

 White blood cells

50–99

10–19

Negative

/hpf

 Casts

Negative

/hpf

 Dysmorphic RBC

Negative

Negative

Negative

 

 Epithelial cells

Negative

Negative

Negative

/hpf

 Bacteria

+

+

Negative

 

Urine culture

E. coli

E. coli

Negative

 
  1. Before: while continuing to take propiverine. After: after taking vibegron for a month
  2. ALB albumin, ALP alkaline phosphatase, ALT alanine transaminase, AST aspartate aminotransferase, BUN blood urea nitrogen, Ca calcium, CL chloride, CRE creatinine, Hb hemoglobin, HCT hematocrit, LDH lactate dehydrogenase, K potassium, Na sodium, PLT platelets, RBC red blood cells, TP total protein, UA uric acid, WBC white blood cells