Fig. 1

Clinical observations during the Patient’s Hospital Admission. Vital signs measured during the patient’s hospital admission including blood pressure, heart rate and temperature. The patient demonstrated high grade cyclical fevers during the admission with associated tachycardia. Improvement in these signs where seen following the administration of steroids on the 13/01/20. The last dose of cabozantinib was taken on 9/1/2020, the day prior to admission. A single dose of cefepime was administered on 10/1/2020