Primary HLH | Secondary HLH | |||
---|---|---|---|---|
Malignant | Nonmalignant | |||
Hematological malignancies | Solid tumors | Autoimmune | Infectious | |
Genetic defects impairing NK and T cell function | Lymphoma Acute leukemias MDS | Lung GI tract Pancreas UG tract | SLE Still’s disease Rheumatoid arthritis | EBV Leishmania CMV SARS-CoV-2 HIV Protozoa Fungal infections TB |