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Table 1 Laboratory data of the patient

From: Pembrolizumab- and ipilimumab-induced diabetic ketoacidosis and isolated adrenocorticotropic hormone deficiency: a case report

Investigation 1 month before admission This admission 6 months after admission Reference range
Plasma glucose, mg/dl 87 794 210 70–99
HbA1C, % N/A 6.5 7.0 4.0–5.6
Beta-hydroxybutyrate, mmol/L N/A 6.3 N/A 0–0.6
Sodium, mmol/L 135 119 140 136–145
Potassium, mmol/L 3.3 6.5 3.4 3.4–4.5
Chloride, mmol/L 97 82 99 95–105
Bicarbonate, mmol/L 28 13 26 22–29
Anion gap, mmol/L 10 24 15 8–16
Blood urea nitrogen, mg/dl 5 39 N/A 7–20
Creatinine, mg/dl 0.75 1.8 0.82 0.7–1.2
Amylase, U/L N/A 60 N/A 20–100
Lipase, U/L N/A 53 N/A 10–60
Anti-GAD, IU/ml N/A 3.09 N/A <  17
Anti-IA2, IU/ml N/A < 7.5 N/A <  7.5
C-peptide N/A < 0.1 N/A 0.9–7.1
8:00 a.m. cortisol, ng/ml N/A 0.6 N/A 3–18
ACTH, pg/ml N/A 21.7 N/A 0–46
FT4, ng/dl N/A 1.22 1.19 0.8–1.8
TSH, μIU/ml N/A 2.94 2.560 0.3–4.1
FSH, IU/L N/A 17.7 13.9 1–8.4
LH, IU/L N/A 19.4 8.1 1–10.5
Testosterone, nmol/L N/A 24.46 14.89 5.9–24.7
IGF-1, ng/ml N/A N/A 66.4 24.6–269
Prolactin, ng/ml N/A 15.9 6.7 2–25
  1. Abbreviations: ACTH Adrenocorticotropic hormone, FSH Follicle-stimulating hormone, FT4 Free thyroxine, GAD Glutamic acid decarboxylase, IA2 Islet antigen 2, IGF-1 Insulin-like growth factor 1, LH Luteinizing hormone, N/A Not available, TSH Thyroid-stimulating hormone Boldface define abnormal value
  2. Boldface define abnormal value