Table 1 Clinical results of multiple myeloma or plasmacytoma metastasizing to the spinal cord in the literature

Di et al.

M

Multiple myeloma

Lower extremity paresthesia and weakness, gait difficulty

T2–T3, T6–T7

T1 w/contrast: enhancing intramedullary mass with prominent associated spinal cord edema

Surgery + RT

N/A

Varettoni et al.

M

Multiple myeloma

Weakness, paraparesis

Thoracic (T1–T2, T5–T6) and lumbar (L2–L3)

T1-weighted: progression of bone lesions, paraspinal plasmacytoma, and diffuse infiltration of the spinal cord

Chemo-RT

1.4

Hans et al.

M

Plasmacytoma

Paresthesia, sensory deficit, progressive tetraparesis

C5–C6

T1/T2 showed mild enlargement of the cord with slight signal intensity from C5–C6. T2 w/contrast enhancement showed small, irregular area of “mild to moderate nodular homogeneous contrast enhancement” at ventral periphery of C5

Chemo-RT

Not reported, but describes significant neurologic deterioration at 10 months

Vale et al.

M

Multiple myeloma

Weakness and paresis of left lower extremity

L1–cauda equina

Sagittal T2 w/contrast showed diffuse infiltration of the cauda equina, extending from L1 to L4. Axial T2 w/contrast showed enhancement of roots at L3 level.

Chemo-RT

11

Touzeau et al.

F

Multiple myeloma

Progressive ataxia

Multiple lesions from C2 to T6

N/A

Chemo-RT

6.75

Gao et al.

M

Plasmacytoma

Progressive lower extremity weakness and abasia. Bilateral abdominal, cremasteric, patellar tendon,and Achilles tendon reflexes absent

T7–T8

T1-weighted: extensive homogeneous isointense signal T6–T10T2-weighted: high-signal T6–T10T1 w/contrast: enhancing irregular lesion in anterior portion of T7–T8Chest, thoracic, and lumbar spine normal on MRI

Surgery

Not reported