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Table 1 Summary of inclusion and exclusion criteria

From: Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature

Inclusion

Exclusion

1. Over the age of 18

2. Diagnosis of POF (two menopausal FSH levels > 40 IU/L or primary or secondary amenorrhea at least for 3–6 months)

3. Normal karyotype 46,XX

4. At least one ovary

5. At least unilateral tubal patency

6. Acceptable uterine anatomy

7. No male infertility

8. Normal thyroid function

9. Planning and/or willing to attempt to become pregnant as part of the experiment

10. No other causes of female infertility

1. Currently pregnant or breastfeeding

2. History or evidence of current gynecologic malignancy within the past 3 years

3. Presence of adnexal masses

4. Major mental health disorder

5. Active substance abuse or dependence

6. Unfit/unwilling to undergo laparoscopy

7. Medical conditions that are contraindicated in pregnancy

  1. FSH Follicle-stimulating hormone, POF Premature ovarian failure