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Table 1 Immunohistochemistry findings

From: Extra-adrenal, non-functional adrenocortical carcinoma presenting with acute abdomen: a case report

Marker

Interpretation

Pan cytokeratin AE1/AE3

Negative

SF-1 (steroidogenic factor 1)

Diffusely positive

Synaptophysin

Diffusely positive

Alpha inhibin

Focally positive

Melan A

Diffusely positive

PAX8 (paired-box gene)

Negative

EMA (epithelial membrane antigen)

Negative

Chromogranin

Negative

S100 protein

Positive in a few tumor cells

CD10

Negative

Vimentin

Negative

Calretinin

Positive

Ki-67 protein

6%

HMB45 (human melanoma black 45)

negative