Table 2 Timeline of events
Timeline | Events |
|---|---|
Day 0 | • Admitted with hypoxia and acute renal failure (on nasal cannula) |
Day 1 | • Worsening of acute hypoxic respiratory failure (on high-flow nasal cannula) |
Day 2 | • Worsening of acute hypoxic respiratory failure (intubated) |
• She underwent bronchoscopy | |
• She became anuric | |
• She was started on pulse dose steroids | |
Day 3 | • She underwent kidney biopsy |
• She was started on intermittent hemodialysis | |
• She was started on cyclophosphamide | |
Day 14 | • She was discharged to subacute rehabilitation facility on cyclophosphamide and prednisone (tapering dose) |
• She was scheduled for out-patient intermittent hemodialysis three times per week (polyuric) | |
Day 45 | • Cyclophosphamide was stopped |
Day 82 | • She was weaned off dialysis (last session) |
Day 113 | • She was given the first dose of rituximab for maintenance therapy |
Day 297 | • She finished her tapering steroids course |
• She was given the second dose of rituximab for maintenance therapy | |
• Kidney function is stable (GFR 49 mL/minute/1.73 m2) |