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Table 1 Summary for laryngoscopic and pathological features for laryngeal nodule and polyps

From: Laryngeal polyp associated with reflux disease: a case report

 

Vocal cord nodule

Vocal cord polyp

Laryngoscopic findings

Sessile, gray white, usually bilateral, in the anterior or middle third of the vocal folds

Pedicled, gray white/red, usually unilateral, located in the anterior and middle thirds of the vocal folds

Size

Usually less than 0.3 cm

Usually greater than 0.3 cm

Pathological features

Parakeratotic, stratified, squamous epithelial covering overlying dense fibrotic stroma

There is prominent basement membrane thickening.

Hemorrhage or hemosiderin-laden macrophages are not usually seen.

Two types:

1. Telangiectatic polyps: orthokeratotic, stratified, squamous epithelial covering overlying numerous thin-walled, dilated vessels in edematous stroma; areas of hemorrhage and hemosiderin-laden macrophages are usually seen

2. Gelatinous polyps: stratified, squamous epithelial covering overlying edematous stroma containing fibrin, proliferating fibroblasts, and few thin-walled vessels