Table 1 Case reports of neoadjuvant imatinib in the treatment of primary dermatofibrosarcoma protuberans
Study | Disease site | Response | Outcome reported |
|---|---|---|---|
Fontecilla et al., 2017 [24] | Scalp with extension to periosteum | Partial response | Tumor completely resected |
Bekerman et al., 2013 [25] | Scapula | Not reported | Patient developed side effects of hypoxemia and shock requiring intubation. Tumor was resected with positive margins. |
Lemm et al., 2008 [26] | Scalp | Partial response | No evidence of recurrent disease after surgical resection |
Wright and Petersen, 2007 [27] | Scalp | Partial response | No evidence of disease 16 months following resection |
Savoia et al., 2006 [28] | Anterior chest wall | Partial response | 8 months of administration with continued reduction in tumor size |
Mehrany et al., 2006 [29] | Left cheek | Partial response | 18 months following resection patient was disease-free |