Lowe syndrome identified in the offspring of an oocyte donor who was an unknown carrier of a de novo mutation: a case report and review of the literature

Table 1 Summary of the cases treated with the affected donor’s oocytes

Cases	MII oocytes	Blasts available	Fresh ET	Result	FRET ET	Live birth	Gender	Affected	Outcome
Couple 1	10	7	2D5	Pregnant	–	2	Male-male	Unaffected	Healthy-healthy
Couple 2	9	7	2D5	Terminated	2D5	1	Male	Unaffected	Healthy
Couple 3	6	4	2D5	Pregnant	–	2	Male-female	Unaffected	Healthy-healthy
Couple 4	4	4	–	–	2D5	2	Male-male	Unknown-affected	1 boy died, 1 alive
Couple 5	12	9	2D5	Pregnant	–	2	Male-female	female unaffected, male affected	Boy operated cataracts

2D5 2 embryos day 5, ET embryo transfer, FRET frozen embryo transfer, MII metaphase II

ISSN: 1752-1947