Fig. 1
From: Neoadjuvant chemotherapy for primary sarcoma of the breast: a case report
a The bulky mass with ulceration prior to neoadjuvant chemotherapy. b Spindle cells with moderate-to-marked cytologic atypia and mitotic activity (high-power view). c Computed tomography shows the enlarged axillary lymph nodes (arrow heads). d, e T1-weighted fat-saturated contrast-enhanced magnetic resonance imaging shows a 78 × 58 mm tumor adjacent to the pectoralis major muscle with enhancement (arrow) (d). The center of the tumor is necrotic (asterisk) based on the low intensity on contrast-enhanced T1-weighted images (d) and high intensity on T2-weighted image (e). The pre-existing necrotic area is considered “pre-treatment necrosis” to differentiate it from post-treatment necrosis caused by neoadjuvant chemotherapy