Coronary microvascular dysfunction pathways | Microvascular dysfunction | Macrovascular dysfunction |
---|---|---|
Non-endothelial dependent | aCoronary flow reserve in response to adenosine 2.8 (normal ≥ 2.5) | bChange in coronary diameter in response to nitroglycerin 0% (normal ≥ 20%) |
Endothelial dependent | cChange in coronary blood flow in response to acetylcholine 48% (normal ≥ 50%) | dChange in coronary diameter in response to acetylcholine − 6% (normal ≥ 5%) |