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Fig. 2 | Journal of Medical Case Reports

Fig. 2

From: Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Fig. 2

a Histologic examination of a tumor biopsy specimen prior to denosumab therapy, showing multinucleate giant cells surrounded by neoplastic stromal cells (hematoxylin and eosin staining; scale bar, 100 μm). b-c Computed tomography images after 6 months of denosumab treatment show a clear border between the vertebral tumor body and soft tissue, indicating calcification of the tumor body (arrowhead). b Coronal view. c Axial view. d Three-dimensional reconstructed image from enhanced computed tomography

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