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Table 2 Endocrinological investigation: rapid cosyntropin stimulation test in January 2018 (day 6 after admission)

From: Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and review of the literature

  Time (min)
0 30 60
Cortisol (μg/dl) < 0.2 1.0 1.4
Aldosterone 5.7 14.1 16.5
  1. Blood samples were taken at 0 (just before) and at 30 and 60 min after synthetic adrenocorticotropic hormone 1–24 (cosyntropin hydroxide 0.25 mg) was intravenously administered in the morning (9 a.m.). The patient had a low plasma adrenocorticotropic hormone level (2.3 pg/ml) and low plasma renin activity (< 0.2 ng/ml/h) just before cosyntropin administration