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Table 1 Laboratory data on admission

From: A novel treatment of hyperinsulinemic hypoglycemia induced by insulin antibodies with alkali administration: a case report

Laboratory test

Reference range

On admission

Blood

 Red blood cells (/μl)

430–540 × 104

313 × 104

 Hemoglobin (g/dl)

14.0–18.0

10.7

 White blood cells (/μl)

4000–8000

4500

 Platelet count (/μl)

15–35 × 104

18.6 × 104

 Reticulocytes (%)

0.7–2.0

0.8

 Plasma glucose level (mg/dl)

70–110

82

 HbA1c (%)

4.9–6.0

7.0

 Glycoalbumin (%)

12.4–16.3

21.4

 Aspartate aminotransferase (U/L)

8–38

13

 Alanine aminotransferase (U/L)

4–44

9

 Lactate dehydrogenase (U/L)

106–211

213

 Alkaline phosphatase (U/L)

104–338

142

 γ-Guanosine triphosphate (U/L)

16–73

31

 Amylase (U/L)

40–129

81

 Total protein (g/dl)

6.7–8.3

7.2

 Albumin (g/dl)

3.8–4.9

4.1

 Urea nitrogen (mg/dl)

8–20

33.4

 Creatinine (mg/dl)

0.6–1.2

2.17

 Uric acid

4–7

7.1

 Sodium (mEq/L)

135–148

145

 Potassium (mEq/L)

3.6–5.0

5.3

 Chloride (mEq/L)

98–108

114

 Fe (μg/dl)

65–157

80

 Total iron-binding capacity (μg/dl)

256–426

289

 Ferritin (ng/ml)

17–291

45.6

 Total cholesterol (mg/dl)

120–220

103

 Low-density lipoprotein cholesterol (mg/dl)

40–119

63

 High-density lipoprotein cholesterol (mg/dl)

42–67

40.1

 Triglycerides (mg/dl)

30–150

40

 C-reactive protein (mg/dl)

0.3

0.05

 Immunoreactive insulin (μIU/ml)

2.2–12.4

> 600

 Free triiodothyronine (pg/ml)

1.71–3.71

2.70

 Free thyroxine (ng/dl)

0.70–1.48

1.10

 Thyroid-stimulating hormone (μIU/ml)

0.35–4.94

2.05

 Cortisol (μg/dl)

6.2–19.4

17.4

 Adrenocorticotropic hormone (pg/ml)

7.2–63.3

23.8

 Adrenalin (pg/ml)

< 100

79

 Noradrenalin (pg/ml)

100–450

913

 Dopamine (pg/ml)

< 20

22

 Glucagon (pg/ml)

70–174

182

 Insulin-like growth factor 1 (ng/ml)

44–177

63

 Growth hormone (ng/ml)

< 2.47

0.61

 Insulin antibodies (U/ml)

< 0.4

> 50.0

 Anti-glutamic acid decarboxylase antibody (U/ml)

< 1.5

0.9

 Anti-islet cell antibody (U)

< 1.25

< 1.25

 Anti-insulinoma-associated 2 antibody (U/ml)

< 0.4

< 0.4

Urine

 pH

5.0–9.0

5.5

 Specific gravity

1.001–1.035

1.022

 Protein

Negative

Negative

 Glucose

Negative

Negative

 Ketone

Negative

Negative

 Albumin-to-creatinine ratio (mg/g Cr)

< 150

34.8

 C-peptide immunoreactivity (μg/day)

29.2–167

40.5

Arterial blood gas

 pH

7.35 ± 7.45

7.343

 Partial pressure of carbon dioxide (mmHg)

32–46

26.7

 Partial pressure of oxygen (mmHg)

74–108

92.5

 Carbon dioxide (mmol/L)

21–29

14.2

 Base excess (mmol/L)

− 4

− 10.1

 Oxygen saturation

92–96

96.4

Human leukocyte antigen DNA typing

 

DRB1*04:05, DRB1*08:03:02

  1. Cr Creatinine, HbA1c Hemoglobin A1c