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Table 1 The patient’s serum and urine biochemistry results

From: Hypodipsic-hypernatremia syndrome in an adult with polycythemia: a case report

 

Ref range

Aug 2012

Nov 2015

Jan 2016

Mar 2016

May 2016

Jun 2016

Feb 2017

Jul 2018

Aug 2018a

Sep 2018b

Serum

 Sodium

138–145 mmol/L

154

147

144

144

143

142

143

147

151

141

 Potassium

3.3–5.3 mmol/L

5.1

5

4.6

4.9

4.8

5

4.4

4.6

5.5

 

 Urea

2.1–7.1 mmol/L

6.4

5.5

5

3.8

4.1

5.8

4.6

5.9

3.9

4.9

 Creatinine

64–104 umol/L

 

107

94

101

93

89

106

110

99

92

 Unadjusted calcium

2.15–2.50 mmol/L

     

2.52

 

2.56

2.72

2.43

 Ionized calcium

1.1–1.3 mmol/L

       

1.21

  

 Leukocyte count

4.0–10.0 × 109/L

8.6

10.8

 

9.0

8.0

8.2

10.1

12.9

8.9

8.8

 Hemoglobin

13.0–17.0 g/dL

17.8

19.3

 

19.1

18.5

18.8

18.6

20.2

19.0

18.1

 Hematocrit

0.40–0.50

0.55

0.60

 

0.60

0.56

0.58

0.58

0.69

0.63

0.58

 Mean cell volume

79.1–98.9 fL

84.9

81.1

 

85.1

84

85.4

85.8

85.9

86.1

84.1

 Platelets

137–373 × 109/L

279

305

 

227

215

234

287

313

301

280

 Albumin

35–52 g/L

52

      

52

  

 Erythropoietin

2.6–18.5 U/L

 

10.7

        

 25-OH-vitamin D

> 72.5 nmol/L

    

< 10.5

     

 PTH

2–7 pmol/L

        

3.6

 

 Renin

2–24 ng/L

        

45.6

 

 Aldosterone

50–640 pmol/L

        

176

 

 Cortisol

130–530 nmol/L

        

130

 

Urine

 Sodium

mmol/L

  

174

       

 Osmolality

50–1200 mOsm/kg.H2O

  

1040

  

792

   

763

  1. Abbreviations: Unadj.calcium unadjusted calcium, 25-OH vitamin D 25-hydroxy vitamin D, PTH parathyroid hormone
  2. aDate of nephrology consultation
  3. bNephrology consultation following 1 week of ~ 2 litres per day of water drinking