Table 1 Previous publications demonstrating diffuse large B-cell lymphoma spontaneous remission
From: Spontaneous remission in diffuse large cell lymphoma: a case report
Case | Age/sex | Site | Size | Staging | CD10 | MUM-1a | B C L-6b | BCL-2c | COOd | Additional findings | Time to SRe (days) | Type of response | Additional treatment | Response duration (months) | Outcome | Ref |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 88/F | LN × 1 Neck | 4 cm | I | + | NA | NA | NA | NA | NA | 105 | CR | None | 21 | Remission | Case |
2 | 72/F | Leg | 3 cm | I | – | + | NA | + | ABCf | EBV-h (intra-tumor CD3, CD4 and CD8 + cells observed) | NA r | PRj | None | 21 | Remission | 4 |
3 | 66/F | Tongue | 2 × 1 cm | I | – | + | – | + | ABC | EBV − | 180 | CRk | None | 84 | Remission | 5 |
4 | 71/F | Breast | 2.6 cm | I | – | + | + | + | ABC | EBV − | 30 | CR | None | 18 | Remission | 6 |
5 | 2/M | Mastoid | Tumor fills sinus cavity | I | – | NA | – | + | ABC | EBV + | 40 | CR | None | 24 | Remission | 7 |
6 | 60/F | Gastric | 1–2 cm | I | NA | NA | NA | – | NA | H. pylori + i EBV − | 139 | CR | Anti-H. pylori m | 15 | Remission | 8 |
7 | 61/M | Gastric | 2 cm | I | NA | NA | NA | – | NA | H. pylori + EBV − | 75 | CR | Roxatidine | 6 | Remission | 8 |
8 | 73/F | Gastric | NA | I | NA | NA | NA | NA | NA | H. pylori + | 40 | CR | Anti-H. pylori n | 30 | Remission | 9 |
9 | 67/F | Max. sinus | 5.1 × 4.2 cm | I | + | + | + | + | ABC p | EBV − | 240 | CR | None | 12 | Remission | 10 |
10 | 61/F | Spleen | Tumor diffusely infiltrated spleen | I | – | + | + | ABC | EBV + | 15 | CR | Prednisone o | 27 | Patient relapsed requiring chemotherapy 27 months after diagnosis | 2 | |
11 | 40/F | Orbit/Conjunctiva | NA | I | NA | NA | NA | NA | NA | EBV + | 40 | CR | None | 6 | Remission | 11 |
12 | 70/M | Jaw | I | NA | NA | NA | NA | NA | NA | 20 | CR | None | 18 | Remission | 12 | |
13 | 82/F | Leg | Multiple 2 cm lesions | II | – | + | + | + | ABC | EBV − | 30 | CR | None | 4 | (Stroke)✝ | 13 |
14 | 85/M | LN × 3. | 0.5–2 cm | II | NA | NA | NA | + | NA | EBV − | 30 | CR | None | 3 | (Pneumonia)✝ | 14 |
15 | 94/F | LN × 3 | 1–2 cm | III | NA | NA | NA | NA | NA | EBV + | 90 | CR | None | 10 | (Pneumonia)✝ | 15 |
16 | 89/M | LN × 2 | 4 cm | III-IV | – | + | – | NA | ABC | EBV + | 60 | CR | None | 20 | (Pneumonia)✝ | 16 |
17 | 85/M | Prostate | Tumor diffusely involved prostate | III-IV | NA | NA | NA | NA | NA | NA | NA | CR | None | 31 | CR | 17 |