From: Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature
Authors | Shapiro et al. [5] | Akosa et al. [19] | Wright et al. [10] | Gormally et al. [6] | Baruchin et al. [20] | Andola et al. [14] |
---|---|---|---|---|---|---|
Number of cases | 13* | 5 | 9 | 11 | 5 | 20 |
Year | 1970 | 1989 | 1991 | 1992 | 1998 | 2017 |
Mean age of presentation | 47.3 years | 39.6 years | 38.66 years | **Mean age of onset: 27.4 years | 36.8 years | 37.2 years |
Number of nodules | One to > 100 | One to 36 | Several | 4–10 (2 cases) | One to multiple | One to multiple |
Size range of nodules | 1 mm to 3 cm | Not stated | A few mm to 2 cm | Up to 2 cm (2 cases) | 2 mm to 1.5 cm | 0.5 to 3.5 cm |
Most common symptoms | Itching (5/13) Asymptomatic (2/13) Breakdown and discharge (4/13) Recurrent (1/13) | Asymptomatic (4/5) Discharge (1/5) | Asymptomatic (mostly) Itching (several) Discharge (in some) | Itching, breakdown and discharge (1/2) Asymptomatic (1/2) | Asymptomatic (4/5) Breakdown and discharge (1/5) | Asymptomatic (16/20) Breakdown and discharge (4/20) |
Clinical diagnosis | Sebaceous cyst (8/13) Cyst (1/13) Not stated (3/13) Calcified fibroma (1/13) | Sebaceous cyst (5/5) | Not stated | Not stated | Not stated | Sebaceous cyst (11/20) Epidermal inclusion cyst (6/20) |
Evidence of epithelial lining in histopathology | No | Yes (1/5) | No | Yes (1/11) | No | No |
Evidence of calcification elsewhere in body | No | No | No | No | No | No |