Fig. 1

a Color fundus at time of diagnosis. Active toxoplasmic lesion is visible over the optic disc despite blurring by vitreitis. Previous pigmented lesions are absent. b A 6 mm swept-source optical coherence tomography crossing the lesion area (see green arrow in a for scan direction): despite blurring, vitreitis nerve fiber swelling and choroidal thickening are well visible. c Superficial retina and (outer retinal layer). d Optical coherence tomography angiography over the lesion shows superficial retinal plexus (c) and choriocapillaris and outer retinal layer (d). Vitreous shading due to inflammatory opacities is clearly visible under the optic disc. e Color fundus 2 months after therapy: inflammatory signs are absent but an atrophic scar is visible. f A 6 mm swept-source optical coherence tomography crossing the lesion (see green arrow in e for scan direction): retinal layers are no longer recognizable at the site of the lesion. Epiretinal membrane appeared possibly due to inflammatory reaction. Choroid has a normal thickness. g and h Optical coherence tomography angiography over the lesion shows only partial retina capillary plexus (g) and deep choroidal vessels (h) reperfusion. In h only deep choroidal vessels are evident in the affected area with persistent choriocapillaris failure