From: Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report
Diagnosis of limbic encephalitis can be made when all foura of the following criteria have been met: | |
1. Subacute onset (rapid progression of less than 3 months) of working memory deficits, seizures, or psychiatric symptoms suggesting involvement of the limbic system | |
2. Bilateral brain abnormalities on T2-weighted fluid-attenuated inversion recovery MRI highly restricted to the medial temporal lobes | |
3. At least one of the following: | |
• CSF pleocytosis (white blood cell count of more than 5 cells/mm3) | |
• EEG with epileptic or slow-wave activity involving the temporal lobes | |
4. Reasonable exclusion of alternative causes |