Fig. 4

Optical coherence tomography B scan images showing the progression of macular schisis in right eye and left eye affected by enhanced S-cone syndrome. a-a’ Horizontal structural optical coherence tomography images of right eye (A) and left eye (A’) show an increase in macular thickness due to the presence of retinal schisis involving the inner and outer nuclear layers. Hyporeflective holes are larger in the left eye, while hyper-reflective vertical septa can be better observed in the right eye. The outer plexiform layer is interrupted in both the right eye and the left eye. b-b′ Swept source structural optical coherence tomography B scans, performed 1 month after the first examination, reveal a decrease in central macular thickness and in size of cystic-like spaces in the right eye. No differences are detectable in the left eye. c-c′ Structural optical coherence tomography B scans, obtained 2 months after the second evaluation, point out a mild increase in retinal thickness and in size of the hyporeflective spaces in the right eye. No change can be seen in the left eye