Fig. 4

The pathological findings. a Tumor cells proliferated in an anastomosing pattern of Hering’s canal-like small glands with an abundant fibrous stroma that replaced the non-cancerous tissue in segment 3 (hematoxylin and eosin staining, × 100). b Small, regular, oval-shaped cells with mild atypia forming the luminal structure were observed in the segment 3 tumor (hematoxylin and eosin staining, × 200). c The tumor in segment 7 was partially surrounded by a thin fibrous capsule and septum. Atypical tumor cells proliferated in a trabecular and pseudoglandular pattern corresponding to moderately differentiated hepatocellular carcinoma (hematoxylin and eosin staining, × 100). On immunohistochemical analysis, segment 3 tumor cells stained positive for d cytokeratin 7 (× 200) and e cytokeratin 19 (× 200). f The membranous region of the lumen of the segment 3 tumor stained positive for epithelial membrane antigen (× 100)