Table 1 Summary of reviewed data on primary amyloidosis with cutaneous manifestation
From: Exceptional mucocutaneous manifestations with amyloid nephropathy: a case report
Case Number | Age/sex | Sicca syndrome as first manifestation/presence prior to diagnosis, months | Cutaneous involvement at time of diagnosis | Organ involvement | Underlying disease | Prognosis in the article/cause of death | Reported year (Reference) |
|---|---|---|---|---|---|---|---|
1 | 52/F | Yes/4Â months | Sicca syndrome and nail dystrophy | Kidney | No | Survived | Present case |
2 | 71/M | Yes/12Â months | Sicca syndrome | Kidney, heart, liver | No | Died (cholestatic hepatopathy) | 1971 [5] |
3 | 68/M | Yes/9Â months | Sicca syndrome | Liver, kidney, heart, pancreas, GI tract, thyroid, prostate, adrenal, testes | No | Died (myocardial infarction) | 1972 [6] |
4 | 58/F | Yes/48Â months | Sicca syndrome and bullous erythema multiform | Liver, heart, peripheral neuropathy | No | Died (unknown) | 1983 [7] |
5 | 63/M | Yes/(unknown) | Sicca syndrome | Kidney, heart | No | Died (heart failure) | 1984 [8] |
6 | 71/M | Yes/6Â months | Sicca syndrome | Kidney | No | Survived | 1988 [9] |
7 | 66/F | Yes/24Â months | Sicca syndrome and purpura, epidermal desquamation | Kidney, heart, lung, GI tract, liver, pancreas, adrenals, thyroid | No | Died (aspiration) | 1991 [10] |
8 | 74/F | Yes/(unknown) | Sicca syndrome | No | No | Survived | 1992 [11] |
9 | 49/M | Yes/(unknown) | Sicca syndrome, multiple ecchymoses | Kidney | Multiple myeloma | Died (GI bleeding, heart failure) | 1993 [12] |
10 | 52/F | Yes/ 24Â months | Sicca syndrome | No | No | Survived | 1994 [13] |
11 | 79/M | Yes/48–60 months | Sicca syndrome, pinch purpura, easy bruising, nail dystrophy | Kidney | No | Survived | 1996 [4] |
12 | 76/M | Yes/6Â months | Sicca syndrome | Kidney, heart, lung, peripheral neuropathy | No | Survived | 1996 [14] |
13 | 62/F | Yes/6Â months | Sicca syndrome | Kidney | No | Survived | 1998 [15] |
14 | 66/M | Yes/60Â months | Sicca syndrome, nail dystrophy, parchment-like hand changes, alopecia | Small fiber neuropathy | No | Survived | 2014 [3] |