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Table 1 A summary of laboratory data

From: Combination therapy of ipilimumab and nivolumab induced thyroid storm in a patient with Hashimoto’s disease and diabetes mellitus: a case report

Blood chemistry

 

Reference

 C-reactive protein (mg/dl)

11.6

≤ 0.20

 Sodium (mmol/L)

135

135–146

 Potassium (mmol/L)

3.9

3.5–4.6

 Chloride (mmol/L)

101

96–110

 Calcium (mg/dl)

8.9

8.2–10.2

 Phosphorus (mg/dl)

3.0

2.5–5.5

 Blood urea nitrogen (mg/dl)

38.3

7.0–20.0

 Creatinine (mg/dl)

0.85

0.7–1.3

 eGFR (ml/minute)

51.9

≥ 60.0

 Total protein (g/dl)

6.1

6.5–8.2

 Albumin (g/dl)

2.8

3.5–5.5

 Total bilirubin (mg/dl)

0.6

0.1–1.2

 Aspartate aminotransferase (U/L)

33

10–35

 Alanine aminotransferase (U/L)

34

5–40

 Alkaline phosphatase (U/L)

245

100–340

 Lactate dehydrogenase (U/L)

284

110–220

y-Glutamyl transpeptidase (U/L)

12

≤ 60

 Creatine kinase (U/L)

132

40–200

Blood count

 

Reference

 Red blood cell (×  104/μL)

341

427–570

 Hemoglobin (g/dl)

10.7

13.5–17.6

 Hematocrit (%)

31.0

39.8–51.8

 MCV (fl)

90.9

82.7–101.6

 Platelet (× 104/μL)

23.7

13.1–36.2

 White blood cell (μL)

13,380

3900–9800

 Neutrophil counts (μL)

11,600

 

Diabetes

 

Reference

 Glucose (mg/dl)

142

70–109

 Hemoglobin A1c (%)

6.7

4.7–6.2

 IRI (μlU/ml)

102.1

3.0–18.0

 CPR (ng/ml)

0.63

0.6–1.8

 GAD antibody

≤ 5.0

≤ 5.0

 IA-2 antibody

≤ 0.4

≤ 0.4

 Urinary albumin (mg/gCr)

281.0

 

Thyroid

 

Reference

 Free triiodothyronine (pg/ml)

31.7

2.2–4.1

 Free thyroxine (ng/dl)

3.43

0.88–1.81

 Thyroid-stimulating hormone (μlU/ml)

0.128

0.35–3.73

 TSH receptor antibody (IU/L)

0.51

< 2.0

 Thyroid stimulating antibody (%)

102

≤ 120

 Thyroglobulin (ng/ml)

48,000

≤ 33.70

 Thyroglobulin antibody (IU/ml)

457

< 28

 Thyroid peroxidase antibody (IU/ml)

8.0

< 16

Endocrine

 

Reference

 Cortisol (μg/dl)

27.5

4.5–21.1

 Growth hormone (ng/ml)

0.13

≤ 2.47

 Somatomedin C (ng/ml)

39

48–177

 Luteinizing hormone (mlU/ml)

18.8

0.8–5.7

 Follicle-stimulating hormone (mlU/ml)

5.8

2.0–8.3

 Free testosterone (pg/ml)

11.0

4.6–16.9

 Prolactin (ng/ml)

9.6

3.6–12.8

 Antidiuretic hormone (pg/ml)

2.7

≤ 2.8

  1. CPR C-peptide immunoreactivity, eGFR estimated glomerular filtration rate, GAD glutamic acid decarboxylase, IA-2 islet antigen 2, IRI immunoreactive insulin, MCV mean corpuscular volume, TSH thyroid-stimulating hormone