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Fig. 1 | Journal of Medical Case Reports

Fig. 1

From: Successful treatment of primary bone marrow Hodgkin lymphoma with brentuximab vedotin: a case report and review of the literature

Fig. 1

Histopathological findings in bone marrow on presentation. Representative photomicrographs of hematoxylin and eosin (HE) and immunohistochemically stained sections of bone marrow. Rectangular area in (a) (HE, × 40) is shown at higher magnification in (b) (HE, original magnification × 400). Reed-Sternberg cell-like cells are present (arrowhead). These cells are positive for CD30 (c, original magnification × 400), Epstein-Barr encoding region in situ hybridization (EBER-ISH) (d, original magnification × 400), CD15 (e, original magnification × 400), Bob-1 (f, original magnification × 400), and PAX-5 (g, original magnification × 400). The small rectangulars in d–g show expression of CD30 in the same field. Arrowheads in f and g identify the CD30 positive malignant cells

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Journal of Medical Case Reports

ISSN: 1752-1947