Table 1 Summary of the five previously reported primary orbital cases of peripheral T-cell lymphoma, not otherwise specified and our case
Case # | Author | Age (y) | Sex | Initial presentation | IHC markers | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
1) | Coupland et al. (1999) [2] | 76 | M | Subconjunctival masses, right eye. Right anterior orbital mass (by radiology) | CD45, CD3, CD4, CD8 | Conjunctival/eyelid – surgical excision Orbital – local irradiation of 36 Gy | Alive 5 years after treatment |
2) | Lee et al. (2006) [3] | 61 | F | Left eyeball pain. Headache | T-cell markers, UCHL-1 | Refused chemotherapy and radiotherapy | Died in a month |
3) | Janatpour et al. (2007) [4] | 44 | M | Right eye diplopia and retro-orbital pain | CD2, surface CD3, CD45RO, CD43, CD4, CD8, TIA-1 granzyme B | CHOP – eight cycles | Alive with resolved masses 3 years after initial visit and treatment |
4) | Chen et al. (2009) [5] | 34 | F | Right orbital painful mass. Protruding right eye | CD3 and CD2 | Radiotherapy | 3-month follow up – proptosis and the protruding mass in the right eye failed to achieve satisfactory resolution |
5) | Amit et al. (2012) [6] | 6 | M | Left eye proptosis. Lagophthalmos | CD45, CD45RO, CD3 | Radiotherapy Chemotherapy – vincristine and adriamycin | Died within 1.5 months of diagnosis |
6) | Present case | 3 | M | Left lower eyelid swelling and ptosis | CD3, CD4, CD8, and CD43 | Chemotherapy | Alive for 12 months after treatment |