Imatinib-induced fulminant liver failure in chronic myeloid leukemia: role of liver transplant and second-generation tyrosine kinase inhibitors: a case report

Table 1 Cases of imatinib-related fulminant liver failure in the literature

Author [reference]	Year	Patient age and sex	Diagnosis	Time between imatinib start and hepatotoxicity	Treatment	Outcome
Talpaz et al. [3]	2002	Not reported	CML	6 days	Drug interruption	Death
Lin et al. [4]	2003	61 years, female	PV	7 weeks	Drug interruption	Death
Cross et al. [5]	2006	46 years, female	CML	77 weeks	LT	Death
Ridruejo et al. [6]	2007	51 years, female	CML	20 weeks	Drug interruption	Death
Thia et al. [7]	2008	45 years, female	CML + chronic hepatitis B	20 weeks	Drug interruption	Death
Perini et al. [8]	2009	47 years, female	CML	72 weeks	LT	Survived
Martínez Pascual et al. [9]	2010	34 years, female	CML	32 weeks	LT	Survived
Harding et al. [2]	2016	30 years, female	CML	20 weeks	LT	Survived
Present case	2017	36 years, female	CML	30 weeks	LT	Survived

Abbreviations: CML chronic myeloid leukemia, PV Polycythemia vera, LT Liver transplant

ISSN: 1752-1947