Table 1 Main clinical process of the first case co-infected by avian influenza A H7N9 and mycoplasma pneumoniae in Kaili, Guizhou province, China
Course | Date | Clinical major events |
|---|---|---|
day 1 | 5 January, 2017 | Fever, cough, abdominal distention, weakness, anorexia |
day 7 | 11 January, 2017 | Went to see doctor, and sputum and throat swabs were collected to be checked for the presence of avian influenza virus |
day 9 | 13 January, 2017 | Admitted to Second Affiliated Hospital of Guizhou Medical University, CT scan showed obvious consolidation and infiltration in bilateral lungs and ground-glass changes in upper area of right lung; and she was diagnosed with pneumoniae, Oseltamivir and meropenem were administered |
day 10 | 14 January, 2017 | Result of neucleic acid testing for H7N9 was positive and the patient was transferred to ICU because of illness deterioration and ARDS. Non-invasive MV. Titer of antibody to mycoplasma pneumoniae was 1:80; |
day 14 | 18 January, 2017 | CHest X-ray showed the infectious focus of bilateral lung partially absorbed. |
day 15 | 19 January, 2017 | Cough again with fewer sputum, other symptoms exacerbated again, increase of moist rale in upper area in right lung; Titer of antibody to mycoplasma pneumoniae rised to 1:160; |
day 19 | 23 January, 2017 | CT scan showed new focus appearing in upper aera while old infultration being absorbed. Titer of antibody to mycoplasma pneumoniae arrived to 1:640, and azithromycin and moxifloxacin were administered. |
day 19 | 23 January, 2017 | Oseltamivir was discontinued because of three continual examinations of neucleic acid for influenza A H7N9 changed to negative |
day 22 | 26 January, 2017 | CT scan shground-glass focus enlarged comparing to that at 12 days before. |
day 25 | 29 January, 2017 | The titer of the antibody decreased to 1:320.Patient’s symptoms were alleviated and moist rales reduced |
day 32 | 4 February, 2017 | CT scan revealed the right upper focus obviously absorbed. Moxifloxacin was discontinued while azithromycin was till continued. |
day 33 | 5 February, 2017 | Discharged from hospital. |
day 35 | 7 February, 2017 | Titier of antibody to M. pneumoniae decreased to 1:80. |
day 41 | 13 February, 2017 | All symptoms disappeared and azithromycin discontinued. |