Table 2 Cases of hearing disorder associated with hydrochlorothiazide retrieved from VigiBase™
From: Hydrochlorothiazide and risk of hearing disorder: a case series
Reaction term | Cases retrieved | Cases with single drug suspect | Cases with positive dechallenge | Cases with positive rechallenge | |
|---|---|---|---|---|---|
1. | Tinnitus | 50 | 29 | 14 | 1 |
2. | Deafness | 23 | 15 | 1 | 0 |
3. | Hearing decreased | 16 | 6 | 2 | 0 |
4. | Vestibular disorder | 4 | 2 | 0 | 0 |
5. | Deafness nerve | 1 | 0 | 0 | 0 |
Total | 94 | 53a | 17 | 1 |