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Table 1 Preclinical studies using mesenchymal stem cells for the treatment of chronic kidney disease [3]

From: Improvement of renal function after human umbilical cord mesenchymal stem cell treatment on chronic renal failure and thoracic spinal cord entrapment: a case report

Disease Source Dose Route Mechanism of action Side effects
Diabetic nephropathy Mice bone marrow 0.5 × 106 cells Intravenous Engraftment/direct effect None
Diabetic nephropathy Human bone marrow 2 × 106 cells Intracardiac Engraftment/direct effect None
Partial nephrectomy Rat bone marrow 1 × 106 cells Intravenous Paracrine effect None
Chronic allograft nephropathy Rat bone marrow 0.5 × 106 cells Intravenous Immunomodulatory effect None
Renal revascularization Allogeneic swine adipose tissue 10 × 106 cells Intrarenal Engraftment/direct effect/paracrine None
Renal artery stenosis Autologous swine adipose tissue 10 × 106 cells Intrarenal Engraftment/direct effect/paracrine None